[Articles] Methylprednisolone in patients undergoing cardiopulmonary bypass (SIRS): a randomised, double-blind, placebo-controlled trial
October 4, 2015
- The Lancet 386, 10000 (2015)
Author: Richard P Whitlock, P J Devereaux, Kevin H Teoh, Andre Lamy, Jessica Vincent, Janice Pogue, Domenico Paparella, Daniel I Sessler, Ganesan Karthikeyan, Juan Carlos Villar, Yunxia Zuo, Álvaro Avezum, Mackenzie Quantz, Georgios I Tagarakis, Pallav J Shah, Seyed Hesameddin Abbasi, Hong Zheng, Shirley Pettit, Susan Chrolavicius, Salim Yusuf, SIRS Investigators
Methylprednisolone did not have a significant effect on mortality or major morbidity after cardiac surgery with cardiopulmonary bypass. The SIRS trial does not support the routine use of methylprednisolone for patients undergoing cardiopulmonary bypass.