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[Case Report Comment] Leukaemic vasculitis from myelodysplastic syndrome in context

Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal stem cell disorders characterised by ineffective haemopoiesis with dysplastic features and the potential to progress to acute leukaemia. Systemic or immune manifestations have been reported in up to 10% of patients and are more frequent in patients with chronic myelomonocytic leukaemia, an overlap disease of MDS and chronic myeloproliferative neoplasms. Autoimmune disorders that accompany MDS include vasculitis, seronegative polyarthritis, neutrophilic dermatosis, inflammatory serous effusions, autoimmune cytopenias, and the presence of cryoglobulins.