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[Comment] Grip strength and mortality: a biomarker of ageing?

Grip strength is a simple but powerful predictor of future disability, morbidity, and mortality. The relation between grip strength and future mortality has been shown, not only in older people1 but also in middle-aged2 and young people.3 The evidence has been summarised in systematic reviews4 and in a meta-analysis.5 However, important questions remain, such as whether the association between grip strength and future mortality is generalisable across countries of widely varying socioeconomic circumstances and, particularly, what might explain the associations.