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[Comment] Oral cholera vaccines in endemic countries

More than 1 billion people are at risk of cholera in endemic countries, with an estimated 2·9 million cases and 95 000 deaths per year.1 A further 87 000 cases and 2500 deaths occur in non-endemic countries.2 Climate change, war, natural disasters, population movement, and urbanisation complicate efforts to control the disease. Although clean water, sanitation, and behaviour change will ultimately be the most critical factors in cholera prevention and control,3 these are difficult to implement in many cholera-endemic countries and a more immediate solution is needed.

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