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[Correspondence] HIV moments and pre-exposure prophylaxis – Authors’ reply

Robert Grant and David Glidden present interesting data from the iPrEx trial.1 By contrast with their findings, the PROUD study2 did not show a major reduction over time in risky sexual behaviour. The figure shows the number of different partners with whom participants reported receptive anal sex without a condom in the 90 days before visits at enrolment, and at 12 months and 24 months. In both the immediate and deferred PrEP groups, about 80% of participants reported one or more partners at 12 months and at 24 months (not necessarily the same individuals).