Sign in with your email address username.


[Correspondence] Infective endocarditis and antibiotic prophylaxis

The study by Mark Dayer and colleagues1 is interesting because it reports an increase in incidence of infective endocarditis in England, but the putative role of the UK National Institute for Health and Care Excellence (NICE) recommendations is scientifically inaccurate and based on an unrealistic hypothesis.2 Figure 3 in the Article1 shows a continued increase in incidence of infective endocarditis without a clear break, similar to that observed with antibiotic prescription decline. During the same period of time, the life expectancy of people in the UK increased by 2·4 years, and therefore, increasing population age corresponds with increased incidence of infective endocarditis.