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[Correspondence] Ixekizumab for psoriasis – Authors’ reply

Concern about depression is highly relevant to the management of psoriasis. The potentially devastating, lifelong psychosocial effect of psoriasis cannot be understated, as reflected by author John Updike and reported in the the scientific medical literature.1 Psoriasis is a chronic, immune-mediated inflammatory disease associated with physical and psychiatric comorbidities, some of which might reflect shared systemic inflammatory processes.2