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[Case Report Comment] Glomerulonephritis from a chronically infected implanted device

In The Lancet, Turgay Saritas and colleagues1 report a case with the valuable reminder that chronic low-grade infection of an implanted device can lead to glomerulonephritis. This complication was first described 50 years ago in patients with implanted cerebral shunts, so-called shunt nephritis,2 but in this case was associated with a newer and increasingly widely used implanted device, the left ventricular assist device (LVAD). Such glomerulonephritis can cause relentless progressive kidney failure, even with antibiotic therapy, especially if circumstances do not allow device removal.