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[Case Report Comment] Vitamin A deficiency in adolescents: rare or underdiagnosed?

In The Lancet, Samantha Simkin and colleagues1 report a case of preventable progressive blindness in an adolescent, caused mainly by vitamin A deficiency. Vitamin A deficiency is considered rare in high-income countries, and although the patient had concurrent systemic infections and mononeuropathy, he was diagnosed only 2 years after the appearance of his first symptoms. After extensive expensive investigations, repeated detailed medical history discovered long-term dietary restrictions. The nutritional disturbances, in addition to corneal signs and recurrent severe infections, raised the possibility of vitamin A deficiency.