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[Clinical Picture] Acral lentiginous melanoma

A 55-year-old woman presented with a non-healing, painless pigmented macule with a superficial ulceration on the left planta, which she said had been there for 6 months. She could not recall any history of trauma and did not report any family history of cutaneous diseases. On physical examination, an irregular pigmented macule with a superficial ulceration and brown haemorrhagic crusts was observed on the left plantar near the heel (figures). A skin biopsy showed a malignant melanoma and immunohistochemical examination of biopsied tissue sections showed positive staining for melanoma associated antigens using the antibodies HMB-45, Melan-A, and S100.