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[Clinical Picture] Langerhans cell histiocytosis presenting as a blueberry muffin rash

A baby boy born at term via spontaneous vaginal delivery to a healthy mother was noted to have a widely disseminated blueberry muffin rash at birth. The pregnancy had been uncomplicated and the patient was otherwise healthy—he was active, afebrile, and feeding well. On examination he had many scattered, firm, non-tender, non-blanching purple papules, (2–6 mm diameter), affecting the face, scalp, trunk, back, diaper region, and arms and legs, including the palms and soles (figure).