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[Clinical Picture] Skull erythropoiesis in a patient with congenital dyserythropoietic anaemia

A 29-year-old woman had a cranial MRI as part of a headache study in April, 2014, which showed widening of the diploic space and displacement of the outer table of the skull, hypointense to grey matter on T1-weighted sequences (figure). She had a history of congenital dyserythropoietic anaemia type III and had needed frequent blood transfusions until the age of 9 years, when she had a splenectomy. Since then she had had annual haematological follow-up and her haemoglobin had remained stable around 90–100 g/L (normal 120–158 g/L).