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[Comment] Acute kidney disease and the community

One simple fact has hindered progress in the fight against kidney disease more than any other—unless complete renal failure occurs, kidney disease is almost asymptomatic. Fatal complications such as cardiovascular disease can occur in patients whose kidney disease is completely unknown to them. Not only is kidney disease silent to the patient, the general public knows little about the problem, and health-care providers might also have insufficient knowledge.1 In 2012, we estimated that 3 million deaths would occur from acute kidney injury worldwide, and called for increased public awareness and research investment.