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[Comment] Coronary artery disease: a dam in the river for ranolazine

Coronary artery disease is the largest contributor to cardiovascular diseases and the number one cause of death in western countries. Percutaneous coronary intervention (PCI) has become the most commonly done interventional procedure in medicine, and coronary artery bypass grafting (CABG) has become one of the most commonly done forms of major surgery.1,2 The number of CABG operations done each year has remained constant, whereas the number of PCI procedures has increased and now accounts for an increasing proportion of revascularisation procedures.