Log in with your email address username.

×

[Comment] Coronary thrombus aspiration: a lesson for clinical medicine

ST-elevation myocardial infarction (STEMI) is most often caused by plaque rupture associated with thrombus formation.1 Embolisation of thrombus is associated with a poor prognosis, and it seems logical that aspiration of thrombus material before coronary stenting should improve outcome. In The Lancet, Sanjit Jolly and colleagues2 report the 1-year results of TOTAL, a multicentre randomised trial of routine manual thrombectomy in 10 732 patients with STEMI, in which patients were randomly assigned to thrombectomy followed by percutaneous coronary intervention (PCI) or PCI alone.

email