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[Comment] Diagnosing myocardial infarction: a highly sensitive issue

The advent of high-sensitivity troponin assays to enable the quantification of troponin concentration in up to 95% of the general population is thought to improve clinical care in patients presenting with suspected infarction.1,2 The application of high-sensitivity troponin assays could be beneficial by enabling the early ruling out of myocardial infarction on the basis of very low troponin concentrations;3–7 precise and rapid diagnosis of myocardial infarction on the basis of troponin-based algorithms8,9 followed by early treatment initiation; and improved risk stratification on the basis of low troponin concentrations that are only detectable by high-sensitivity assays.