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[Comment] Effective treatment of progressive MS remains elusive

Relapsing-remitting multiple sclerosis (RRMS) has been treatable for over 20 years and increasingly effective therapies continue to be developed.1 Unfortunately, therapies that convincingly affect the progressive phase of MS have yet to be identified. The International Progressive MS Alliance was formed to combat this multifaceted problem.2 This alliance of several MS societies, scientists, foundations, pharmaceutical sponsors, and individuals has been working together since 2012 to accelerate the understanding of, develop therapies for, and undertake clinical trials in progressive MS.