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[Comment] Estimating the global prevalence of hepatitis B

The substantial global burden of hepatitis B virus (HBV) infection is increasingly recognised. Recent estimates suggest that HBV infection caused 686 000 deaths in 2013,1 placing HBV in the top 20 causes of human mortality. Despite this, comprehensive reviews of data regarding the burden of chronic HBV at regional and national levels have been scarce. This is an area of particular importance in view of the global diversity in chronic HBV prevalence, and the disproportionate burden experienced by people living in low-resource settings.