Log in with your email address username.

×

Important notice

doctorportal Learning is on the move as we will be launching a new website very shortly. If you would like to sign up to dp Learning now to register for CPD learning or to use our CPD tracker, please email support@doctorportal.com.au so we can assist you. If you are already signed up to doctorportal Learning, your login will work in the new site so you can continue to enrol for learning, complete an online module, or access your CPD tracker report.

To access and/or sign up for other resources such as Jobs Board, Bookshop or InSight+, please go to www.mja.com.au, or click the relevant menu item and you will be redirected.

All other doctorportal services, such as Find A Doctor, are no longer available.

[Comment] Ethical considerations in noise-induced hearing loss research

Animal studies have shown that glutathione peroxidase 1 (GPx1) is highly expressed in the sensory epithelium of the inner ear, and a targeted mutation of the gene for Gpx1 was found to increase noise-induced hearing loss in mice.1 Based on these observations and given the overlapping role of oxidative stress and cellular injury in noise-induced hearing loss, Jonathan Kil and colleagues2 examined the prophylactic benefits of the administration of ebselen, a GPx1 mimic, in a randomised trial of 83 participants who were exposed to 4 h of standardised sound calibrated to cause a temporary elevation of hearing thresholds, the results of which are published in The Lancet.

email