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[Comment] Expansion of the treatment toolbox for mitral regurgitation

In The Lancet, Fabien Praz and colleagues1 report their preliminary experience with the PASCAL mitral repair device and its success among 23 patients, most of whom were not considered anatomically suitable for conventional percutaneous mitral repair.2 The authors did a multicentre, prospective, observational, first-in-man study, collecting data from seven tertiary care hospitals in five countries. Eligible patients were those with symptomatic, severe functional, degenerative, or mixed mitral regurgitation who were denied other surgical or transcatheter options.