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[Comment] Fetal alcohol spectrum disorder: complexity from comorbidity

Every day, in the USA alone, 100–500 children are estimated to be born with fetal alcohol spectrum disorders (FASD).1 Most will never be diagnosed with FASD, and those who are will often wait years for a correct diagnosis. Misdiagnosis is often due to an underappreciation of the role of damage to the CNS, which is a unifying concept in FASD. The expression of the FASD phenotype is both age and development dependent. Increasing prevalence of comorbidity is key to understanding the typical increase in FASD severity over time.