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[Comment] Gastroenterology and hepatology: a call for papers

Remarkable advances have been made in gastroenterology and hepatology in recent years. For instance, the development of direct-acting antiviral treatments for hepatitis C virus raises the prospect of eliminating such infections—cost and access notwithstanding.1 And exciting progress is being made in harnessing the immune system to tackle previously hard-to-treat gastrointestinal cancers.2,3 But other challenges remain, or are arising. For example, as a result of increases in obesity, non-alcoholic steatohepatitis (NASH) is predicted to replace infection as the leading cause of cirrhosis, hepatocellular carcinoma, and liver transplant in the USA in the next 10–20 years;4 similar transitions are likely to take place elsewhere if global trends in obesity continue.