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[Comment] Invasive management of acute coronary syndromes

Invasive versus non-invasive treatment in patients with non-ST-elevation acute coronary syndromes has been shown to reduce fatal and non-fatal events in the FRISC-II,1 RITA-3,2 and TACTICS-TIMI 183 trials, and in meta-analyses,4,5 with positive results extending to 5 years.6 In The Lancet, the FRISC-II investigators present the 15 year outcomes of their study.7 In FRISC-II, 2457 patients with non-ST-elevation acute coronary syndromes were randomly assigned between 1996 and 1998 to receive an early invasive strategy with revascularisation within 7 days or a non-invasive strategy with invasive procedures for recurrent symptoms or exercise-induced ischaemia.

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