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[Comment] Not all probiotic strains prevent necrotising enterocolitis in premature infants

In The Lancet, Kate Costeloe and colleagues1 report the outcome of the highly awaited PiPS trial, assessing the potential preventive effect of the probiotic bacterium Bifidobacterium breve BBG-001 on necrotising enterocolitis, late-onset sepsis, and mortality in premature infants.1 Necrotising enterocolitis remains among the most devastating diseases encountered in premature infants. The cause of necrotising enterocolitis is an excessive inflammatory process in the intestinal mucosa that presents clinically with feeding intolerance, abdominal distension, and bloody stools.