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[Comment] Offline: Paolo Macchiarini—science in conflict

The resignation of Anders Hamsten as Vice-Chancellor of the Karolinska Institute has accelerated a growing sense of emergency within the Swedish biomedical science community. His departure comes during the same week that the Royal Swedish Academy of Sciences issued an unprecedented statement accusing Paolo Macchiarini of “ethically indefensible working methods”. The Academy is the body that awards annual Nobel Prizes in Physics, Chemistry, and Economics (the Nobel Prize in Physiology or Medicine is awarded by the Karolinska Institute, hence the likely acute embarrassment at the tarnished reputation of one of the world’s most respected scientific centres).