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[Comment] Oral corticosteroids for multiple sclerosis relapse

Corticosteroids are the oldest immunological treatment for multiple sclerosis, but are no longer used as disease-modifying agents because of the serious adverse effects associated with chronic administration and the development of more effective disease-modifying drugs. Nevertheless, high-dose intravenous steroid is the best available treatment to induce accelerated remission from a multiple sclerosis attack, and to limit the residual neurological deficits.1,2 Clinical reports about the positive effects of corticosteroids on relapses are supported by MRI studies.