[Comment] Oral fexinidazole for human African trypanosomiasis
Human African trypanosomiasis caused by Trypanosoma brucei gambiense (g-HAT) is transmitted to human beings by tsetse flies in western and central Africa. Human beings are the only significant reservoir of the protozoan parasite, and disease control is focused on the detection and treatment of infected individuals, with or without vector control. Screening for cases can be passive (individuals are examined at fixed centres) or active (mobile teams travel to villages). The card agglutination test for trypanosomiasis and recently developed rapid diagnostic tests are the serological methods used for screening.