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[Comment] Pharmacogenetics of lithium response: close to clinical practice?

The beliefs that genes are the root of diseases and that genomics has the potential to help us screen, diagnose, predict, and treat disease are particularly compelling in cancer research.1,2 However, human genomic research focusing on mental disorders and other complex illnesses is at a fairly early stage, with no best approach yet identified to study complex diseases such as bipolar disorder. Genes associated with risk for bipolar disorder have been searched with candidate gene and genome-wide association approaches.