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[Comment] Prevention of fractures in patients with osteoporosis

Patients with osteoporosis who have previously had fragility fractures have the highest risk of recurrent fractures, and 10–20% of those with recent fractures will re-fracture within just 2 years.1 Yet most patients who have had fractures are untreated and those who are tend to be treated conservatively, namely with an oral bisphosphonate.2 Antiresorptive drugs, such as bisphosphonates and denosumab, and bone-forming agents, such as teriparatide, both increase bone mineral mass and reduce fragility fractures in patients with osteoporosis.

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