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[Comment] Reprogramming psychiatry: stem cells and bipolar disorder

Psychiatry continues to lag behind the rest of medicine in its ability to understand its disorders and develop new effective treatments. Hot on the tail of the increasingly robust and informative genetic leads provided by genome-wide association studies, hopes have been raised by two further developments. The first is a concerted research move away from current syndromal diagnoses towards identification of the underlying neural and cognitive processes, as exemplified by the US National Institute of Mental Health’s Research Domain Criteria initiative.