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[Comment] Stretching the carotid sinus to treat resistant hypertension

Around a quarter of adults have hypertension, and by 2025, the number affected might be more than 1·5 billion people worldwide.1 Despite important advances in pharmacotherapy in the past 40 years, resistant hypertension—that is, persistently raised ambulatory blood pressure despite treatment with at least three antihypertensive drugs, including a diuretic—occurs in about 13% of treated adults.2 Optimisation of treatment is crucial in people with resistant hypertension because of the increased risk of cardiovascular disease.