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[Comment] Surveillance of Zika virus infection and microcephaly in Brazil

Zika virus has been spreading rapidly in Brazil and the Americas, with a sharp increase in the number of notified microcephaly cases since September, 2015.1,2 Based on the high number of cases, and the association between Zika virus infection and microcephaly,3,4 WHO on Feb 1, 2016, declared a Public Health Emergency of International Concern.5 Recently, animal models have shown that the Brazilian Zika virus strain causes intrauterine growth restriction and microcephaly.6