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[Comment] Target blood pressure in patients at high cardiovascular risk

High blood pressure is the major risk factor for disease and premature death worldwide, and the association between blood pressure and fatal cardiovascular complications is well established.1,2 The risk increases continuously from a blood pressure of 90–114 mm Hg systolic and 60–74 mm Hg diastolic. There is no increase in risk with low values, and the risk associated with higher blood pressures increases with age and differs with specific cardiovascular disease conditions. Antihypertensive therapy reduces cardiovascular morbidity and all-cause mortality, and a target blood pressure less than 140/90 mm Hg is advised for most patients.