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[Comment] The clinical challenge of disappearing stents

Drug-eluting stents have become the standard of care for patients undergoing percutaneous coronary intervention.1 Initial concerns about late stent thrombosis with first-generation drug-eluting stents were largely mitigated by the technological advances of the second generation.2 Rates of restenosis and thrombosis with these newer generation stents are impressively low in the first year of use.2 Yet this type of system has disadvantages, including impaired coronary vasomotion, development of early neoatherosclerosis, and long-term retention of a polymer-coated metallic cage, which in some cases might preclude bypass grafting of failed stented segments.