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[Comment] Tradition and innovation in development of a Zika vaccine

In response to the urgent need for a vaccine to prevent congenital syndromes associated with Zika virus, the scientific community has responded swiftly. Several vaccine technologies are in development. In The Lancet, Kayvon Modjarrad and colleagues1 and Martin R Gaudinski and colleagues2 report results of phase 1 clinical trials of candidate Zika vaccines. It has been less than 2 years since the association between Zika virus infection and microcephaly was established in Recife, Brazil,3,4 and to have multiple promising vaccine candidates in so short a time is impressive.