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[Comment] Tuberculosis—getting to zero

Reviewing research The Lancet has published on the global tuberculosis epidemic, one will be struck by how little the situation has changed over the years, and how the same calls to action get repeated from one year to the next. For decades, a piecemeal approach with a narrow treatment focus and a cost imperative has prevailed. The result? A global epidemic of disease. For more than a decade the global tuberculosis incidence rate has declined, but only slowly by about 1·65% annually.1,2 Meanwhile, the worst legacy of this disease has become multidrug resistance.