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[Comment] Use of morphine before retinopathy of prematurity examinations

Understanding optimum ways to reduce pain and stress associated with medical procedures in paediatric populations reflects health-care providers’ inherent mandate to do no harm. This is especially urgent in vulnerable preterm populations who undergo an average of 12 painful procedures daily while receiving neonatal care,1 given our increasing understanding of the adverse effects of early pain exposure on later neurodevelopment and behaviour.2 Several interventions—such as breastfeeding,3 parent–infant skin-to-skin contact,4 and sweet-tasting solutions5—have been shown to reduce biobehavioural pain response associated with needle-related procedures.