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[Comment] Women and opioids: something different is happening here

An opioid crisis is raging in the USA, spreading across Canada, and there is increased opioid prescribing and access to high potency opioids such as fentanyl in other countries.1 Action is demanded through national initiatives and strategic plans2 to address the underlying causes of this epidemic, implement effective treatments for opioid use disorders (OUD), and support research that will improve interventions. However, current planning overlooks gender differences in opioid use that have meaningful implications for preventing misuse and treating pain and OUD.