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[Correspondence] Acute bacterial meningitis in adults – Authors’ reply

We thank Frédéric Jacobs and colleagues for their interest and comment on our Seminar about acute bacterial meningitis in adults.1 As Jacobs and colleagues say, immunochromatographic tests (ICTs) for pneumococcal antigens have been assessed as a potential diagnostic test and do indeed have utility when molecular methods are unavailable. ICTs have also been shown to have considerable benefits over latex agglutination.2 However, some of the limitations to antigen testing are that the sensitivity has varied and might be as low as 50%,3–5 it only allows the detection of one organism, and, of course, will not provide any information about antimicrobial susceptibilities.

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