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[Correspondence] Antibiotic-impregnated catheters for prevention of bloodstream infection – Authors’ reply

Jaiben George argues that use of antibiotic-impregnated central venous catheters in paediatric intensive care contributes to the emergence of antibiotic resistance, which might diminish the effectiveness of systemic antibiotics given to children. The similar rates of antibiotic resistance in all three groups in the CATCH trial probably reflects background rates of resistance.1,2 The trial was underpowered to detect differences related to type of central venous catheters; nevertheless, there have been no published reports of increased antibiotic resistance, despite use of antibiotic-impregnated central venous catheters in adults over the past 20 years, and numerous trials involving these catheters.

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