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[Correspondence] Association between Guillain-Barré syndrome and Zika virus infection – Authors’ reply

We thank the correspondents for their comments on our study linking Zika virus to Guillain-Barré syndrome.1 About the concern regarding the non-specificity of Brighton criteria for diagnosing Guillain-Barré syndrome, we would like to emphasise that besides having typical clinical manifestations, all patients tested during the first week (37 [88%] of 42; the five remaining were in intensive care) had nerve conduction abnormalities, 39 (93%) of 42 patients had increased cerebrospinal fluid protein concentrations, and 16 (38%) of 42 required intensive care, substantiating the objective nature and severity of the disease.

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