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[Correspondence] Ceftolozane-tazobactam versus levofloxacin in urinary tract infection

Florian Wagenlehner and colleagues (May 16, p 1949)1 report an industry-sponsored randomised controlled trial comparing ceftolozane-tazobactam with levofloxacin in complicated and upper urinary-tract infection. The trial results should be questioned because the design was biased against the control drug and breached the guiding principles of antibiotic stewardship.2