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[Correspondence] Central arteriovenous anastomosis and hypertension

We are concerned by the Article by Melvin Lobo and colleagues (April 25, p 1634)1 who created arteriovenous fistulae to lower blood pressure in hypertensive patients. We warn against optimistic conclusions: the groups were not well balanced (differing prevalences of coronary artery disease, previous cerebrovascular events, and calcium channel blocker use), and the main effect was only in-office blood pressure. This effect reminds us of the eventually irreproducible positive results of initial renal denervation studies,2 probably showing an effect of treatment adherence and white coat hypertension.