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[Correspondence] Corticosteroid therapy for pneumonia

Respiratory tract infections (RTIs) cause millions of deaths worldwide each year.1 Despite the availability of appropriate antibiotic therapy, treatment of all forms of RTIs is associated with major long-term morbidity and mortality. This outcome could be attributable to excessive, sustained inflammatory responses with consequential pulmonary damage, dampening of effective immune responses, and pulmonary dysfunction, all of which retard recovery and cure. Adjunct, host-directed therapies that modulate destructive inflammatory responses could improve morbidity and mortality rates and prevent serious long-term sequelae.