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[Correspondence] Ebola vaccination – Authors’ reply

In his linked Comment1 about the interim results of the Ebola ça suffit trial,2–4 Philip Krause makes several important points. 90 clusters were included in the planned interim analysis of this cluster randomised trial: 48 clusters were assigned to immediate vaccination with the rVSV-ZEBOV Ebola vaccine and 42 clusters were assigned to delayed vaccination with rVSV-ZEBOV. In the immediate vaccination group, no cases of Ebola virus disease were noted with symptom onset at least 10 days after randomisation, whereas in the delayed vaccination group there were 16 cases from seven clusters.