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[Correspondence] Fixed-dose combinations for hypertension

Globally, 1·4 billion people have hypertension, of whom less than 15% have their blood pressure appropriately controlled1 and, as a result, elevated blood pressure is a leading cause of death globally, killing more than 10 million people a year. In low-income and middle-income countries, more than 70% of the treated patients with hypertension have uncontrolled blood pressure. One major reason for low levels of control is that most patients only receive monotherapy,1,2 although evidence suggests that most patients require two drugs or more to achieve optimal and sustained blood pressure control.