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[Correspondence] Gender-questioning children deserve better science

The health of transgender children is addressed with imprecise language and overplayed empirical evidence in new Australian guidelines1 and in an Editorial (June 30, p 2576).2 Sex has a biological basis, whereas gender is fundamentally a social expression. Thus, sex is not assigned—chromosomal sex is determined at conception and immutable. A newborn’s phenotypic sex, established in utero, merely becomes apparent after birth, with intersex being a rare exception.

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