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[Correspondence] Hormone therapy and ovarian cancer – Authors’ reply

Users of menopausal hormone therapy are at greater risk of developing ovarian cancer than otherwise similar non-users. Our meta-analyses1 of virtually all the available epidemiological evidence showed a highly significantly increased risk of ovarian cancer in current users of menopausal hormone therapy; the excess risk declined after hormone use ceased, although a small excess persisted for about a decade after stopping long-duration use.1 In the few studies of fatal ovarian cancer, findings were typical of those reported for incident disease.

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