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[Correspondence] Infective endocarditis and antibiotic prophylaxis

Mark Dayer and colleagues1 report an increase in incidence of infective endocarditis in England beginning in 2008, which corresponds with a sharp decrease in antibiotic prescription for infective endocarditis prophylaxis after publication of UK National Institute for Health and Care Excellence (NICE) guidelines. As acknowledged by the authors, this temporal association is not proof of a causal association. Nevertheless, these findings will lead to reconsideration of the possible usefulness of antibiotic prophylaxis, despite a consistent trend since 2002 to restrict or end it.