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[Correspondence] Mechanical chest compression in the PARAMEDIC trial – Authors’ reply

Pierre-Nicolas Carron and colleagues1 enquire about the effect of mechanical chest compression in patients transported to hospital with continuing chest compressions during the PARAMEDIC trial. This effect was not reported in the original trial because the subgrouping variable (transport to hospital with ongoing chest compression) arises after randomisation and might be affected by the study treatments. Bias is expected in this comparison.